Progress in the study of LncRNA associated with epithelial mesenchymal transition in gastric cancer
Epithelial mesenchymal transformation(EMT)refers to the biological process of transforming epithelial cells into cells with mesenchymal phenotype.It is considered to be a key step in tumor invasion and metastasis.LncRNA is a kind of RNA that does not encode protein.Its main function is to control the transcription and expression of down-stream genes by regulating the complex activity related to gene transcription and other complex mechanisms,including related signal pathways in the process of EMT.Studies have shown that EMT is closely related to the primary invasion,secondary invasion and metastasis of gastric cancer.This paper reviews the research progress of EMT related LncRNA in gastric cancer.
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