To investigate the effect of clinical pharmacists participating in anticoagulation management on oral warfarin anticoagulation in patients with non-valvular atrial fibrillation
Objective To explore the effect of clinical pharmacists'participation in anticoagulation management on the anticoagulation effect of oral warfarin in patients with non-valvular atrial fibrillation.Methods From 132 patients with non-valvular atrial fibrillation admitted to our hospital from January 2019 to September 2020,66 cases were randomly selected as the observation group,receiving joint anticoagwlation management by clinical pharmacists,nurses and residents.The other 66 cases were selected as the control group,receiving routine anticoagulation management by residents and nurses during hospitalization.The intervention of anticoagulant drug monitoring by clinical pharmacists was conducted to explore the effect and safety of warfarin anticoagulation management.Results The INR compliance rate of the observation group patients is higher than that of the control group,and the difference is statistically significant(χ2=8.19,P<0.05);The compliance of patients taking warfarin in the observation group(89.39%)was better than that in the control group(57.56%),and the difference was statistically significant(χ2=17.94,P<0.001);The incidence rate of bleeding events in the observation group(9.09%)was lower than that in the control group(31.82%),with a statisti-cally significant difference(χ2=4.59,P<0.05).Conclusion The participation of clinical pharmacists in anticoagula-tion management service can significantly improve the efficacy and safety of anticoagulation in patients with NVAF.Therefore,it is necessary to strengthen the monitoring and management service of clinical pharmacists for anticoagulation prevention and treatment.
Non-valvular atrial fibrillationWarfarinAnticoagulation drug
万方数据
维普
