Limb shaking as the first symptom in neuronal inclusion body disease:a report of one case and literature review
Objective Analyze the clinical,imaging and cutaneous pathological features of neuronal intranuclear in-clusion body disease(NIID),improve understanding of NIID and reduce misdiagnosis and missed diagnosis for clini-cians.Methods The clinical data,diagnosis and treatment process of the patient with NIID in our hospital were retro-spectively analyzed,combined with literature analysis.Results The patient was initially diagnosed as Parkinson's dis-ease due to limb trembling in the left upper limb.After the treatment with dopamazid,there was no obvious relief,and then he felt dizziness and walking instability gradually.Brain MRI showed high signal on DWI image.NIID was finally di-agnosed by skin biopsy and genetic testing.Conclusion NIID is rare and highly heterogeneous.Imaging examination should be improved as soon as possible for definite diagnosis of unexplained limb shaking.
Neuronal inclusion body diseaseLimb shakingHeterogeneity of clinical manifestations
万方数据
维普
