Effects of bone strengthening treatment for elderly patients with osteoporosis and vertebral compression fracture
Objective This study was aimed to evaluate the effectiveness of bone strengthening treatment for elderly patients with osteoporosis vertebral compression fracture.Method A retrospective control study was conducted to collect patients with osteoporosis and vertebral compression fractures who were hospitalized in the Geriatrics Department of Xiqing Hospital in Tianjin from June 2020 to June 2022.A total of 71 eligible patients were collected,and the patients were divided into two groups based on their treatment plans.The control group only received conventional oral calcium carbonate D tablets;while the observation group received a combination of calcium carbonate D tablets,calcitriol cap-sules,and alendronate tablets.The pain intensity was evaluated using the Visual Analog Scale(VAS),and the degree of dysfunction was assessed using the Oswestry Disability Index(ODI).The study was designed to compare the difference of BMD,VAS scores and ODI scores between the two groups before surgery and at the last follow-up,and record the inci-dence of secondary fractures and adverse reactions in both groups.Result At the last follow-up,the difference in bone mineral density(BMD)values between the observation group and the control group before and after treatment was 0.4±1.3 vs-0.2±1.0(t=1.785,P=0.023).Both groups experienced pain improvement,but the difference in VAS scores was not statistically significant(-3.4±1.3 vs-2.9±1.7;t=-0.042,P=-0.742).When comparing the difference in ODI scores,the observation group had a score of-40.3±12.7,while the control group had a score of-14.2±13.8(t=-3.155,P＜0.001).The incidence of new vertebral fractures in the control group was 15.6%(5/32),while that in the observation group was only 2.6%(1/39).In the observation group,6 patients experienced upper abdominal pain and nausea.After proper guidance on medication usage,the symptoms were significantly alleviated.Conclusion The com-bined use of Calcium tablets,Calcitriol and Alendronic Acid was in favor of increasing bone density and improve social function.A long-term bone strengthening treatment has a significant effect in preventing recurrent vertebral fractures.
万方数据
维普
