Alcohol is a depressant of the central nervous system,and long-term heavy drinking can lead to alcohol dependence(AD).Alcohol dependence is a complex and serious mental illness that can lead to disturbances in daily physical,mental and social functioning.Currently,the prevalence of alcohol dependence is approximately 2.6%,and the lack of effective clinical prevention strategies,treatment,and rehabilitation options is a major factor contributing to the growing global health burden of alcohol dependence.Long-term repeated drinking and withdrawal can cause changes in brain structure and function,cause neuropsychological cognitive function damage,and lead to dementia in severe cases,which seriously endangers human physical and mental health.The etiology of cognitive impairment caused by alcohol dependence is complex,and oxidative stress plays a key role in the cognitive impairment of alcohol dependence.This review focuses on the relationship between cognitive impairment caused by alcohol dependence and oxidative stress,in order to provide some references for the diagnosis and treatment of cognitive dysfunction caused by alcohol dependence.
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