Study on medication rules of Chinese patent medicine for children with upper respiratory tract infection based on data mining
Objective To explore the medication rules of oral Chinese patent medicine for children with upper respiratory tract infection,so as to provide scientific basis for clinical rational use of Chinese patent medicine and ensure the safety of drug use in children.Methods Totally 3600 prescriptions of Chinese patent medicine for children with upper respiratory tract infection in outpatient department of pediatrics were extracted from Jan.to Dec.2022.Data mining was conducted on the medication data,and the use of Chinese patent medicine,rationality of application and unreasonable reasons were counted and analyzed.Results Among 3600 prescriptions of Chinese patent medicin,15 Chinese patent medicines were used,and 1.238 kinds of Chinese patent medicine were used per capita;The top three Chinese patent medicines in terms of drug use frequency were Chaiyin Granules,Lanqin Oral Liquid and Lianhua Qingwen Capsules,and the top three drug categories were heat-clearing prescriptions,exterior-relieving prescriptions and expectorant cough relieving and asthma relieving prescriptions,with the main dosage forms being granules and oral liquids;In terms of combined medication,the two combination drugs of Chaiyin Granules and Amoxicillin and Clavu-lanate Potassium Dispersible Tablets were the most widely used,and the strongest association rule was found between Ibuprofen Tablets and Chaiyin Granules;There were 52 pieces of irrational prescriptions,with an irrational rate of 1.44%,mainly involving inappropriate indications,inaccurate dosage or course of treatment,inappropriate combination therapy,and repeated use of drugs.Conclusion Chinese patent medicine was widely used in pediatrics,and its clinical application was basically reasonable.Chinese medicine focused on treating both manifestation and root cause of upper respiratory tract infection,and with unique advantages,it reduced the use of Western antibiotics and ensured the healthy growth of children.
ChildrenChinese patent medicineUpper respiratory tract infectionMedication ruleData miningRational drug use