Research progress on cervical cancer immunotherapy
Among women's malignant tumors,cervical cancer is a more typical gynecological tumor.There are no obvious symptoms and signs of cervical cancer in the early stage.Patients in the middle and late stages are treated by sur-gery,radiotherapy and chemotherapy,and the prognosis is relatively poor.The rapid development of molecular biology and immunology has discovered the pathogenesis of tumors.Immunotherapy has become a new method of treating various malignant tumors and a research hotspot for cervical cancer treatment.This article summarizes the research progress of HPV vaccine,secondary T cell therapy(TILs,TCR-T,CAR-T),tumor immune checkpoint inhibition therapy(PD-1/PD-L1 pathway inhibitor,CTLA-4 checkpoint inhibitor)and multiple immunotherapy combined treatment of cervical cancer.
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