Mitochondria are involved in regulating multiple cellular biological behaviors,including energy metabolism,oxidative stress and calcium regulation.The kidney is one of the organs with the mostabundant mitochondria in body,and mitochondrial quality is essential for renal function.Mitochondrial network is highly regulated,including fission,fusion,mitophagy,and mitochondrial biogenesis.This review will focus on the research progress of mitophagy in kidney injury.