Advances in basic research promoting endogenous repair of the anterior cruciate ligament
Anterior cruciate ligament(ACL)injury is one of the common ligament injuries in the field of sports medicine.Due to its limited endogenous repair capacity,reconstruction surgery has become the preferred treatment method.However,postoperative ligament function is difficult to fully restore,and various complications are prone to occur,which can reduce the patient's quality of life.With the accumulation of experience in ligament repair and the development of tissue engineering and regenerative medicine,non-operative reconstruction methods and biological enhancement techniques have become research hotspots,especially in animal models,to explore treatment approaches that improve the effectiveness of anterior cruciate ligament injury repair.This article reviews the progress of basic research promoting endogenous repair of the anterior cruciate ligament,which can be summarized into six aspects:growth factor therapy,stem cell therapy,gene therapy,bioengineering,pharmacological therapy,and physical therapy.
国家科技期刊平台
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