Functional differences between the fetal and maternal sides of the placenta based on MRI intravoxel incoherent motion imaging techniques
Objective:To investigate whether there are differences in placental function between the fetal side and maternal side,as well as the correlation between the functional changes in these two parts and the gestational weeks.Methods:The intravoxel incoherent motion imaging(IVIM)was employed to collect data on placental perfusion fraction(f),diffusion coefficient(D),and pseudo-diffusion coefficient(D*)from the maternal side and the fetal side of 75 placentas at gestational weeks 23-40,respectively.Differences between the maternal and fetal sides of the placenta were compared by the Wilcoxon matched-pairs signed rank test,and regression methods for curve estimation and curve fitting analysis were employed to explore the correlation between the fetal and maternal side data and gestational weeks.Results:There were statistically significant differences in f and D between the maternal and fetal sides of the placenta.Maternal lateral perfusion fraction(y)was correlated with gestational week(x),showing a quadratic correlation.The goodness of fit for the curve R2 was 0.121,with the equation y=0.635-0.0155x+0.0001x2.The difference value between the fetal-side perfusion fraction minus maternal-side perfusion fraction,fin-fout(y),was correlated with x,showing a quadratic correlation,and the goodness of fit for the curve R2 was 0.295,with the equation y=-1.318+0.080x-0.001x2.Conclusion:There are significant differences between the function of the fetal and maternal sides of the placenta,and the perfusion fraction of the maternal side of the placenta correlates with gestational week.
万方数据
维普
