无水乙醇、泡沫硬化剂治疗儿童大型静脉畸形的疗效比较
Absolute ethanol versus foam hardening agent for large venous malformations in child patients:comparison of efficacy
赵磊 1丁语 1徐伟洋 1皮梦奇 1徐淼1
作者信息
- 1. 450000 河南郑州 郑州大学附属儿童医院
- 折叠
摘要
目的 探讨无水乙醇、泡沫硬化剂治疗儿童大型静脉畸形的临床疗效.方法 回顾性分析60 例大型孤立性静脉畸形患儿的临床资料.将先注射无水乙醇再注射泡沫硬化剂作为A组(n=30),先注射泡沫硬化剂再注射无水乙醇作为B组(n=30),对比两组患儿的临床疗效、并发症、注射次数及无水乙醇用量等.结果 A、B两组的总有效率均为 100%.A组显著有效率为 63.33%(19/30),B组显著有效率为90%(27/30),差异有统计学意义(P＜0.05).无水乙醇用量A组为(10.30±3.19)mL,B组为(6.73±2.06)mL;注射次数A组为(3.57±1.01)次,B组为(2.63±0.61)次,差异均有统计学意义(均P＜0.05).两组均无严重并发症发生,水疱发生率A组 30%(9/30),B组为 6.67%(2/30),差异有统计学意义(P＜0.05).结论 无水乙醇、泡沫硬化剂联合应用治疗儿童大型静脉畸形,可以增加疗效,减少无水乙醇用量,降低并发症;尤其先注射泡沫硬化剂再注射无水乙醇疗效更佳.
Abstract
Objective To discuss the clinical efficacy of absolute ethanol and foam hardening agent in the treatment of large venous malformations(VM)in child patients.Methods The clinical data of a total of 60 child patients with solitary large VM were retrospectively analyzed.The child patients were divided into group A(n=30)and group B(n=30).Patients in group A received absolute ethanol injection followed by foam hardening agent injection,while patients in group B received foam hardening agent injection followed by absolute ethanol injection.The clinical efficacy,complications,mean number of injections and mean dosage of absolute ethanol were compared between the two groups.Results The total effective rate in both group A and group B was 100%.The markedly effective rate in group A and group B was 63.33%(19/30)and 90%(27/30)respectively,and the difference was statistically significant(P＜0.05).In group A and group B,the mean dosage of absolute ethanol was(10.30±3.19)mL and(6.73±2.06)mL respectively,the mean number of injection was(3.57±1.01)times and(2.63±0.61)times respectively,and the differences in the above two indexes were statistically significant(both P＜0.05).No serious complications occurred in either group.The incidence of blisters in group A and group B was 30%(9/30)and 6.67%(2/30)respectively,and the difference was statistically significant(P＜0.05).Conclusion For large VM in child patients,combination use of absolute ethanol and foam hardening agent can improve the curative efficacy,reduce the dosage of absolute ethanol,and lower the incidence of complications.In addition,the therapeutic mode of foam hardening agent injection followed by absolute ethanol injection can achieve better efficacy.(J Intervent Radiol,2024,32:28-32)
关键词
无水乙醇/泡沫硬化剂/静脉畸形/硬化疗法Key words
absolute ethanol/foam hardening agent/venous malformations/sclerotherapy引用本文复制引用
出版年
2024
NETL
NSTL
万方数据