摘要
目的 探讨股动脉穿刺介入术后穿刺部位出血的危险因素.方法 检索从建库至2022年12月31日中国知网、万方、维普、中国生物医学文献服务系统数据库(CBM)、PubMed、Medline、The Cochrane Library、EMbase、Web of Science数据库中关于经股动脉穿刺介入术后穿刺部位出血危险因素的观察性研究,包括横断面研究、病例对照和队列研究文献.采用Newcastle-Ottawa量表(NOS)评分对纳入研究的文献质量进行评价,应用RevMan 5.3软件对文献数据进行Meta分析.结果 最终纳人文献8篇(总样本量35 250例),术后出血组患者1410例,非出血组33 840例.Meta分析结果显示,高龄(OR=2.71,95％CI=2.17～3.38)、女性(OR=4.26,95％ CI=1.08～16.89)、高血压(OR=2.48,95％ CI=1.69～3.63)、肥胖(OR=2.33,95％CI=1.59～3.42)、使用溶栓剂/抗凝剂/血小板拮抗剂(OR=2.95,95％ CI=2.24～3.89)、人工按压(OR=6.78,95％CI=1.34～34.43)是股动脉穿刺介入术后穿刺部位出血的危险因素.结论 高龄、女性、高血压、肥胖、使用溶栓剂/抗凝剂/血小板拮抗剂、人工按压是股动脉穿刺介入术后穿刺部位出血的危险因素.
Abstract
Objective To explore the risk factors for bleeding at the puncture site after femoral artery puncture intervention.Methods A computerized retrieval of observation studies,including cross-sectional studies,case-control studies,and cohort studies,about the risk factors for bleeding at the puncture site after femoral artery puncture intervention from the databases of China National Knowledge Infrastructure(CNKI),Wanfang,VIP,China Biomedical Literature Service(CBM),PubMed,Medline,The Cochrane Library,EMbase and Web of Science was conducted.The retrieval time period was from the establishment of the database to December 31,2022.Newcastle-Ottawa scale(NOS)was used to evaluate the quality of the included studies,and RevMan5.3 software was used to make meta-analysis of the literature data.Results A total of 8 articles with a total sample size of 35 250 patients were included in this analysis.There were 1 410 patients in the postoperative bleeding group and 33 840 patients in the non-bleeding group.The results of the meta-analysis showed that the aged(OR=2.71,95％ CI=2.17-3.38),female(OR=4.26,95％ CI=1.08-16.89),hypertension(OR=2.48,95％CI=1.69-3.63),obesity(OR=2.33,95％ CI=1.59-3.42),use of thrombolytic agents,anticoagulants or platelet antagonists(OR=2.95,95％ CI=2.24-3.89),manual compression(OR=6.78,95％ CI=1.34-34.43)were the risk factors for the bleeding at the puncture site after femoral artery puncture intervention.Conclusion The aged,female,hypertension,obesity,use of thrombolytic agents,anticoagulants or platelet antagonists,and manual compression are the risk factors for the bleeding at the puncture site after femoral artery puncture intervention.(J Intervent Radiol,2024,33:314-320)
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