At present,transcatheter arterial chemoembolization(TACE)is a common treatment for advanced unresectable hepatocellular carcinoma(HCC).In recent years,hepatic artery infusion chemotherapy(HAIC)with oxaliplatin plus fluorouracil and leucovorin(FOLFOX)regimen has been used in the treatment of advanced HCC in China.HAIC in combination with molecular targeted drugs and/or immune checkpoint inhibitors has yielded encouraging results.This paper aims to describe the theoretical basis,development history and research progress of TACE and HAIC,to analyze and compare the efficacy and adverse events of TACE and HAIC,so as to provide a reference for the choice of treatment timing and therapeutic regimen for patients with advanced HCC.
hepatocellular carcinomatranscatheter arterial chemoembolizationhepatic artery infusion chemotherapymolecular targeted drug therapy
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