Objective To discuss the clinical efficacy of ultrasound-guided endovascular suture(UGES)for the treatment of multi-cavity femoral artery pseudoaneurysms(MFAP).Methods The clinical data of a total of 5 patients with femoral artery pseudoaneurysm(FAP)with the number of pseudoaneurysm lesions ≥2,who were admitted to the Qujing Municipal First People's Hospital of China to receive UGES treatment between June 2022 and December 2023,were retrospectively analyzed.The clinical efficacy and complications during the follow-up period were recorded and analyzed.Results Successful UGES treatment was accomplished in all the 5 patients.None of the femoral artery pseudoaneurysm had a recurrence,rupture,or infection in one month after UGES treatment.No femoral artery stenosis or lower limb arteriovenous thrombosis occurred.Conclusion For the treatment complicated MFAP,UGES is clinically safe and effective.