Endovascular interventional therapy is a common local treatment for hepatic malignancies,which requires high performance of the acquisition,recognition,and processing of intraoperative images.Cone-beam computed tomography(CBCT)is a volumetric imaging technique,it can provide additional information about the lesions and the tumor-feeding arteries.At present,CBCT has been gradually employed in interventional treatment of liver malignancy,meanwhile its technique has been constantly innovated and developed.CBCT technology has already been recommended by a number of consensus and guidelines both at home and abroad.For recent years,single-stage CBCT imaging technology has been matured and it has been widely used in clinical practice,besides,a number of novel CBCT imaging techniques improve the imaging quality of CBCT and expands the application scope of CBCT imaging technology.This paper aims to introduce the single-stage CBCT imaging technique with its clinical advantages,to illustrate some newly-developed CBCT imaging techniques,to summarize the present comprehensive utilization of CBCT imaging technology in endovascular interventional therapy of hepatic malignancy,and to discuss the shortcomings and limitations of CBCT in the clinical application.