Chemical composition of Ni3Al-based alloy was designed based on the"Cluster-plus-glue-atom model"to improve its room temperature properties,the microstructure,mechanical properties and corrosion resistance of the alloys were investigated.The results show that the alloys before and after annealing are composed of β phase,α phase and matrix phase γ'.After annealing at 1050 ℃ for 24 h,β phase and α phase are evenly distributed in the matrix of Ni5Co5Cr2Al2.5Ti1.5 alloy,which improves not only the mechanical properties(maximum compression rate of 29.35%,yield strength of 1796 MPa,hardness of 546.35 HV),but also induces galvanic corrosion,enhances the passivation effect and improves the corrosion resistance(impedance of 7.74 × 104 Ω,corrosion potential of-0.055 V(vs SCE),corrosion current density of 5.93 × 10-7 A/cm2)of the alloys.The alloys designed in this paper show significant improvements in mechanical properties and corrosion resistance compared to Ni3Al.This work provides a new avenue for research in the composition design of high-temperature alloys.