实用心电学杂志2024,Vol.33Issue(1) :19-23.DOI:10.13308/j.issn.2095-9354.2024.01.004

碎裂QRS波及左心室肥大对原发性高血压患者室性心律失常的预测价值

Predictive value of fragmented QRS complex and left ventricular hypertrophy for ventricular arrhythmias in patients with primary hypertension

许悦悦 吕聪敏 张萌 李小妞 赵心珠
实用心电学杂志2024,Vol.33Issue(1) :19-23.DOI:10.13308/j.issn.2095-9354.2024.01.004

碎裂QRS波及左心室肥大对原发性高血压患者室性心律失常的预测价值

Predictive value of fragmented QRS complex and left ventricular hypertrophy for ventricular arrhythmias in patients with primary hypertension

许悦悦 1吕聪敏 1张萌 1李小妞 1赵心珠1
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作者信息

  • 1. 450003 河南 郑州,郑州大学第二附属医院心内科
  • 折叠

摘要

目的 探讨碎裂QRS波及左心室肥大对原发性高血压(primary hypertension,PH)患者室性心律失常(ventricular arrhythmia,VA)的预测价值.方法 选取261 例PH住院患者,均行常规心电图、动态心电图、动态血压、超声心动图等检查.根据动态心电图检查结果,将所有入选患者分为VA组(129 例)和非VA组(132 例).比较和分析各组患者的一般资料、生化指标等检验检查结果.将经单因素分析后有意义的数据纳入多因素Logistic回归,分析碎裂QRS波、左心室肥大与VA的关系,并绘制ROC曲线.结果 VA组低密度脂蛋白胆固醇水平、碎裂QRS波阳性率、左心室后壁厚度、左心室舒张末期内径均高于非VA组(P<0.05).Logistic回归分析结果显示,碎裂QRS波与左心室肥大是PH患者发生VA的独立危险因素.ROC曲线分析表明,碎裂QRS波与左心室肥大联合预测VA发生的风险优于单独预测效果.结论 碎裂QRS波与左心室肥大是PH患者发生VA的独立危险因素.两者联合对VA发生风险的预测效果优于单独预测效果.

Abstract

Objective To investigate the predictive value of fragmented QRS complex and left ventricular hypertrophy for ventricular arrhythmia(VA)in patients with primary hypertension(PH).Methods A total of 261 inpatients with PH were selected,and they all underwent routine electrocardiography,ambulatory electrocardiography(AECG),ambulatory blood pressure monitoring,echocardiography,and other examinations.Based on the results of AECG,the enrolled patients were divided into VA group(129 cases)and non-VA group(132 cases).Laboratory and examination results of general information and biochemical indicators were compared and analyzed between the two groups.Significant variables identified through univariate analysis were included in multivariate Logistic regression analysis to explore the relationship between fragmented QRS complex,left ventricular hypertrophy,and VA.Results In the VA group,the level of low-density lipoprotein cholesterol,positive rate of fragmented QRS complex,left ventricular posterior wall thickness,and left ventricular end-diastolic diameter were all higher than those in the non-VA group(P<0.05).Logistic regression analysis revealed that fragmented QRS complex and left ventricular hypertrophy were independent risk factors for VA in patients with PH.ROC curve analysis indicated that the combination of fragmented QRS complex and left ventricular hypertrophy was superior to either of the individual indicator in predicting the risk of VA.Conclusion Fragmented QRS complex and left ventricular hypertrophy are independent risk factors for the occurrence of VA in patients with PH.The combination of the two is superior to either of the individual indicator in predicting the risk of VA.

关键词

碎裂QRS波/左心室肥大/原发性高血压/室性心律失常

Key words

fragmented QRS complex/left ventricular hypertrophy/primary hypertension/ventricular arrhythmia

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基金项目

河南省医学教育研究课题(YJSJY201971)

出版年

2024
实用心电学杂志
江苏大学

实用心电学杂志

影响因子:0.648
ISSN:2095-9354
参考文献量2
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