Atrial fibrillation(AF)has become an important disease that endangers the health of middle-aged and elderly people in China,and it is related to the risk of stroke and death.At present,pathophysiological mechanisms such as atrial structural remodeling,electrical remodeling,inflammation,autonomic nervous system disorders,and non-coding RNA may explain the occurrence and development of AF.The treatment of AF mainly includes anticoagulation,conversion of sinus rhythm,and control of ventricular rate.In addition,anti-inflammatory,autonomic nerve intervention and genomics intervention therapy may become new types of therapies for AF.This article reviews the research progress in the pathogenesis and treatment of AF.
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