Analysis of correlation between ankle-brachial index and ventricular repolarization parameters in patients with type 2 diabetes mellitus
Objective To investigate the relativity between ankle-brachial index(ABI)and ventricular repolarization parameters among hospitalized patients with type 2 diabetes mellitus(T2DM).Methods Retrospective analysis was performed on the clinical data of inpatients with T2DM who had undergone ABI inspection.According to ABI values,they were divided into abnormal ABI(ABI≤0.9 or≥1.3)group(82 cases)and normal ABI(0.9＜ABI＜1.3)group(88 cases).Clinical data,and echocardiographic and ventricular repolarization parameters were recorded and analyzed for the patients of both groups.Results Patients in the abnormal ABI group were older and had longer course of diabetes compared with the normal ABI group,and the differences were both statistically significant(both P＜0.01).Additionally,the abnormal ABI group showed elevated values in Tpeak-Tend(Tp-e)interval,corrected QT interval(QTc),Tp-e/QTc ratio,and frontal QRS-T(fQRS-T)angle compared with the normal ABI group,all with statistically significant differences(all P＜0.05).According to Spearman correlation analysis,there were significant correlations between ABI and Tp-e interval(r=-0.393,P＜0.01),QTc(r=-0.198,P＜0.01)or Tp-e/QTc ratio(r=-0.557,P＜0.01).Conclusion ABI bears a negative correlation separately with main ventricular repolarization parameters,namely Tp-e interval,QTc,and Tp-e/QTc ratio.Therefore,for T2DM patients with abnormal ABI,more attention should be paid on the risk of malignant arrhythmias.
type 2 diabetes mellitusankle-brachial indexventricular repolarization parametercorrelation analysis
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