Pay attention to diagnosis and treatment of cardiovascular adverse reactions associated with immune checkpoint inhibitors
Immune checkpoint inhibitors(ICIs)occupy a core position in tumor immunotherapy,and greatly improve the prognosis of tumor patients.However,with the deepening of clinical practice,it has been found that ICIs can not only activate the immune system,but also cause many adverse reactions,especially leading to a variety of cardiovascular toxicity and increased cardiovascular mortality.This paper reviews the clinical manifestations,pathogenesis,diagnosis and treatment,etc.of ICIs-induced cardiovascular toxicity,which provides evidences for preventing cardiovascular injury and improving cardiac function.