Research advances in pericardial diseases associated with immune checkpoint inhibitors
Immune checkpoint inhibitors(ICIs)have been widely applied in the clinical treatment of various malignant tumors by blocking the tumor immune escape.However,it is followed by increasing immune-related adverse events caused by ICIs.As common ICIs-related cardiovascular adverse reactions,pericardial diseases lead to a relatively high mortality at the acute phase.This article introduces the research progress in recent years on the epidemiology,pathogenesis,clinical characteristics,and treatment principles of ICIs-related pericardial diseases,in order to deepen the clinicians'understandings of this disease.