淀粉糖苷表面活性剂急性毒性实验
Acute Toxicity Texts of the Starch-based Alkyl Polyglucosides Surfactant
王青宁 1耿来红 1杨明俊 2李澜 1张飞龙 1刘芳1
作者信息
- 1. 兰州理工大学石油化工学院,甘肃兰州 730050
- 2. 兰州理工大学生命科学与工程学院,甘肃兰州 730050
- 折叠
摘要
按照GB7919-87对淀粉糖苷表面活性剂进行了小白鼠急性皮肤毒性实验、家兔完整皮肤和破损皮肤急性皮肤刺激实验、多次皮肤刺激实验、一次眼刺激实验、多次性眼刺激实验、皮肤致敏实验.评价了淀粉糖苷表面活性剂对眼睛和皮肤的局部应用安全性.结果表明,C0810、C1200、C1214淀粉糖苷表面活性剂无急性皮肤毒性,无皮肤刺激性,无眼刺激性,致敏率为0,无皮肤致敏反应.淀粉糖苷皮肤局部应用安全可靠.
Abstract
In order to evaluate the safety of starch-based alkyl polyglucosides, the acute dermal toxicity test of mice, acute eye and skin irritation tests on rabbits, multiple eye and skin irritation and skin allergy tests on rabbits were conducted according to the standard GB7919 -87. The results show that the C0810,C1200,C1214 starch-based alkyl polyglucosides surfactant had no acute dermal toxicity and eye stimulation. They didn't cause irritation or allergy to skin. The allergic reaction rate is 0. Thus,they are more secure and reliable in practice.
关键词
淀粉糖苷/表面活性剂/急性皮肤毒性/皮肤刺激/眼刺激/皮肤致敏Key words
starch glucoside/surfactant/acute dermal toxicity/skin irritation/eye irritation/skin sensitization引用本文复制引用
基金项目
甘肃省攻关项目(2GS052-A41-005-03)
出版年
2012
NETL
NSTL
维普
万方数据