Collagen,an essential tissue protein in creatures with comprehensive origin and types,as well as excellent biocompatibility,biodegradability and biological activity,is an important functional material.However,the application of unmodified collagen is limited due to its poor physical and chemical properties such as thermal stability,mechanical strength,and enzyme resistance.Therefore,how to improve collagen properties via modification has attracted much attention of researchers.Amino groups on the side chain of collagen provide strong crosslinking ability and positive charge.As a result,The application of collagen can be further expanded by amination,which enhances the positive sites and surface charge of collagen.In this background,the properties and main modification methods of collagen were described in detail.The latest application progress of amino-modified collagen in biomedicine,environmental management and the leather industry was then summarized.Finally,the future development of amino-modified collagen in a clean chrome-free leather tanning system was prospected.
NETL
NSTL
万方数据
维普
