摘要
氨基酸金属有机框架是指含有氨基酸单元的有机配体与金属离子共同参与合成的具有周期性结构的材料.氨基酸作为蛋白质的组成成分,具有绿色环保、生物相容性良好、种类多样、价格低廉等优点,将其引入金属有机框架(MOFs)可以赋予材料特殊的柔性结构、丰富的活性位点、优良的应用性能等特征.该文综述了氨基酸MOFs的结构维度分类,介绍了氨基酸MOFs的主要合成方式,包括溶剂热法、机械化学合成法、微波加热辅助法,进一步阐述了材料的性能调控,重点介绍了这类材料在手性拆分、催化、吸附等领域的应用.最后,通过分析当前氨基酸金属有机框架材料存在的稳定性不好、结构难以预测等问题,对其未来在生物医药领域的研究重点进行了展望.
Abstract
Amino acid metal-organic framework is a kind of material with periodic structure,which is synthesized with the participation of metal ions and amino acids as organic ligands.As a component of protein,amino acids have the advantages of the green environmental protection,good biocompatibility,variety and low price.Introducing them into MOF can endow materials with special flexible structure,rich active sites,special structure and other characteristics.The review first elaborates the structure-dimensional classification of amino acid MOFs.Secondly,the main synthesis methods of amino acid MOF include solvothermal method,mechanochemical synthesis method,microwave heating auxiliary method.The performance regulation of materials is then further explained.On this basis,the applications of these materials in chiral separation,catalysis,adsorption and other fields are introduced emphatically.Finally,by analyzing the problems of poor material stability,unpredictable structure,the future research of amino acid metal-organic framework materials is prospected.
基金项目
国家自然科学基金(21878209)
山西省重点研发计划(201903D321100)
山西省基础研究计划(自由探索类)面上项目(20210301123101)
维普
万方数据