Porphyrinoid-based metal-organic framework for phototherapy application
Porphyrinoid-based metal organic framework,featured with a crystal structure formed by the coordinating self-assembly between metal clusters and porphyrin ligand or porphyrinoid family compounds,has shown promising application potential in the field of photochemistry and biological medicine due to its combination of good photophysical properties and biocompatibility of porphyrinoid molecules as well as its periodic and controllable structure.In particular,with the excellent performance of porphyrinoid molecules fully utilized,the porphyrinoid metal organic framework plays an important role in killing harmful cells in human bodies with adjunctive photo-assisted therapy including photokinetic and photothermal treatments.Herein,the structure of porphyrinoid-based metal organic framework was introduced,followed by summarization on the recent development of porphyrinoid-based metal organic framework in the biomedical field including anti-tumor and anti-bacterial treatments.The performance improvement of porphyrinoid-based metal organic framework type photosensitizers in comparison to porphyrinoid molecules,and the diverse functions derived from the different type of porphyrinoid metal organic framework were emphatically discussed.Finally,the future development potentials of porphyrinoid metal organic framework were also proposed.
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