Research progress on photothermal nanomaterials in antibacterial applications
The appearance of drug-resistant bacteria has led to a sharp increase in clinical incidence and mortality,significantly impacting human life and medical systems.In order to address the problems of drug-resistant bacteria mutations and the prolonged process in antibiotics investigation,the development of new antibiotic methods is essential and urgent.Photothermal therapy(PTT),a novel antibacterial technique,utilizes solar energy to generate thermal energy,which raises the temperature in the local area so as to eliminate the bacteria.With its unique antibacterial mechanism,PTT reduces the possibility of drug-resistant bacteria formation,thus providing a special advantage in the antibacterial field,with various photothermal nanoparticles and nanocomposites the key.In this review,the latest research on the design and synthesis of various photothermal agents(PTAs)was discussed,followed by summarization on their development and applications.Finally,the existing problems and the future directions of PTT antibacterial applications were analyzed to provide reference experience for the design and synthesis of PTAs materials with efficient antibacterial properties.