Preparation,characterization and properties of photothermal/photodynamic synergistic antibacterial carbon dots
Copper-doped carbon dots(CuQACDs)with photothermal/photodynamic synergistic antibacterial ability were prepared from one-step hydrothermal reaction of allyl trimethyl ammonium chloride(QAC)and CuCl2·2H2O,characterized by TEM,Zeta potential,FTIR,XPS,Raman spectrum and UV-Vis adsorption spectrum,and evaluated on their antibacterial properties by Escherichia coli(E.coli)and Staphylococcus aureus(S.aureus).The results showed that CuQACD2 prepared with n(QAC)∶n(Cu2+)=1∶2 exhibited a well-dispersed spherical nanostructure with an average hydrated particle size of about 4.9 nm and a Zeta potential of 8.17 mV.Under the irradiation of 808 nm laser with a power density of 1.5 W/cm2,CuQACD2 showed a photothermal conversion efficiency of 21.7%,with ROS produced in bacterial cells.CuQACD2 with a mass concentration of 1.50 g/L displayed significant antibacterial activity on E.coli and S.aureus,the E.coli and S.aureus cell survival rates were 1.67%and 1.06%,respectively,after irradiation for 10 min with 808 nm laser at 1.5 W/cm2.
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