摘要
目的：探讨3.0T动态增强磁共振扫描(DCE-MRI)联合弥散加权成像(DWI)诊断三阴性乳腺癌的临床价值。方法收集我院2011年9月-2013年9月收治的经病理证实为三阴性乳腺癌(观察组)18例、非三阴性乳腺癌患者(对照组)58例，回顾性分析其DCE-MRI及DWI图像资料。对比两组患者肿瘤病灶的强化模式、TIC-曲线特征及ADC值3项指标的差异。结果(1)MRI强化特点：观察组以环形强化为主要特征，而对照组以不均匀强化为主要特点，差异具有统计学意义(P<0.05)。(2)TIC-曲线观察组多为流出型，对照组多为流出型及平台型，差异无统计学意义(P>0.05)。(3)DWI通过测量ADC值来量化分析，观察组ADC值较对照组低，差异有统计学意义(P<0.05)。结论三阴性乳腺癌以环形强化为主、ADC值较低，联合3.0T DCE-MRI及DWI有助于提高对三阴性乳腺癌的诊断。
Abstract
Objective To discuss the clinical study of 3.0T dynamic contrast-enhanced magnetic resonance (DCE-MRI) in combination with diffusion-weighted imaging(DWI) in diagnoses of triple negative breast cancer. Methods Eighteen cases of triple negative(observation group,OG) and fifty-eight cases of non-triple negative breast cancer (control group,CG),confirmed by pathol-ogy,are enrolled in this study,from September 2011 to September 2013. We perform a retrospective analysis of these two groups patients’ imaging data of DCE-MRI and DWI. We compare the enhancement features,TIC-curve and ADC value between these two groups. Results (1)Ring enhancement as the main feature appears in OG,and irregular enhancement in CG. The difference is statistically significant(P<0.05). (2) TIC-curves show outflows in OG and outflows platform type in CG,mostly. There is no signifi-cant differences between the two groups(P>0.05). (3) DWI quantitatively analysis by measuring the ADC value. And the ADC value of OG is smaller than that of CG. The difference is statistically significant (P<0.05). Conclusion The three negative breast cancer mostly shows ring enhancement with low ADC value. The combination of 3.0T DCE-MRI and DWI is helpful to improve the diag-noses of triple negative breast cancer.
NETL
NSTL
维普
万方数据