Application of nasal high flow humidifying oxygen therapy in children with congenital heart disease after surgery
Objective To observe the application of nasal high flow humidifying oxygen therapy in children after congenital heart disease.Methods From January 2019 to November 2023,80 cases of children under 1 year old after operation of congestive congenital heart disease in pediatric Heart Center of our hospital were selected as the study subjects,and were divided into nasal high flow humidification oxygen delivery group(HFNC group)and nasal continuous positive airway pressure ventilation(nCPAP group)according to different non-invasive ventilation support methods after operation withdrawal,with 40 cases in each group.The postoperative mechanical ventilation time,ICU stay time,blood gas index,respiratory rate(RR),secondary intubation rate,postop-erative atelectasis and postoperative infection rate were compared between the two groups.Results The mechanical ventilation time and ICU stay time in HFNC group were shorter than those in nCPAP group(P＜0.05).The interaction between time point and group had statistically significant effects on PaCO2,PaO2/FiO2 and RR of the children(P＜0.05).A separate effect analysis showed that there was no statistically significant difference in PaCO2,PaO2/FiO2 and RR between the two groups before extubation(P＞0.05).PaCO2,PaO2/FiO2 and RR were compared between HFNC group and nCPAP group at 1 h,6 h,12 h,24 h and 48 h after extubation(P＜0.05).The rate of secondary intubation and complications in HFNC group were lower than those in nCPAP group(P＜0.05).Conclusion Nasal high flow humidification oxygen therapy can effectively improve the oxygenation index and respiratory rate of children with congenital heart disease after surgery,avoid secondary intubation,shorten the ICU stay time,promote the re-habilitation process of children,and obtain good social benefits.
Postoperative congenital heart diseaseNasal high flow humidified oxygen therapyBlood gas indexPostoperative infection
万方数据
维普
