Application of echocardiography and myocardial injury markers in cardiac injury assessment of uremia patients
Objective To investigate the application value of echocardiography and myocardial injury markers in the evalua-tion of heart injury in patients with uremia.Methods From May 2021 to December 2022,60 patients with uremia hemodialysis in our hospital were selected to be included in the uremia group,and 60 healthy subjects were selected to be included in the control group during the same period.All included subjects were examined by echocardiography to detect serum markers of myocardial in-jury.The differences of echocardiographic indexes and serum markers of myocardial injury between uremia group and control group were compared.Results In uremia group,echocardiographic indicators were left atrial,left ventricular diameter(LAD,LVD),right atrial,right ventricular end-diastolic diameter(RAD,RVDD),diastolic,systolic septal thickness(IVSD,IVSS),left ventricular pos-terior diastolic thickness(LVPWd),left ventricular posterior systolic thickness(LVPWs),and left ventricular systolic diameter(LVD)S)level was higher than that of control group(P<0.05);The early diastolic peak velocity(E)and late diastolic peak veloci-ty(A)of mitral valve in uremia group were higher than those in control group,and the E/A ratio was lower than that in control group(P<0.05).Ventricular systolic function stroke output(SV),cardiac output index(CI)and left ventricular ejection fraction(LVEF)in uremia group were lower than those in control group(P<0.05).The levels of B-type brain natriuretic peptide(BNP),troponin T(cTnT),creatine kinase isoenzyme(CK-MB)and homocysteine(Hcy)in uremia group were higher than those in control group(P<0.05).Conclusion Echocardiography can accurately and intuitively observe the cardiac structure and function,and the high expression of serum markers of myocardial injury can reflect the occurrence of cardiac injury.Both are safe and reliable methods to evaluate the cardiac status of uremia hemodialysis patients.
uremiaHeart injuryEchocardiographyMarkers of myocardial injury
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