首页|中医治疗期间心超评价心外膜脂肪厚度与冠心病及其严重程度的相关性研究

中医治疗期间心超评价心外膜脂肪厚度与冠心病及其严重程度的相关性研究

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目的 探究中医治疗期间心超评价心外膜脂肪厚度(EAT)与冠心病及其严重程度的相关性.方法 回顾性分析2021 年 7 月至 2023 年 8 月于心血管科行冠状动脉造影检查的 300 例参检者的临床资料,依据冠状动脉造影检查结果分为冠心病组(200 例)及无冠心病组(以下简称"对照组",100 例),再根据病变累及冠状动脉数量将冠心病组分为单支病变组(100 例)、单支以上病变组(100 例).均行冠状动脉造影及超声心动图检查,对比各组生化指标及心功能指标水平、EAT检查结果,另分析EAT与冠心病生化及心功能指标水平.结果 各组总胆固醇(TC)、甘油三酯(TG)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、空腹血糖(FBG)、左室射血分数(LVEF)水平比较,差异无统计学意义(P>0.05);单支以上病变组左房内径及EAT均大于单支病变组及对照组,差异有统计学意义(P<0.05).Pearson相关性分析显示,EAT与患者年龄、TG水平、左房内径均呈正相关(r=0.312、0.418、0.834,P=0.003、<0.001、<0.001),与HDL-C呈负相关(r=-0.229,P=0.001).结论 中医治疗期间心超评估EAT与冠心病病情严重程度之间存在一定相关性,通过观察EAT水平变化可判断冠心病患者病情变化情况,且心超检查具有简便、无创、快捷等特点,适用于冠心病初期筛查,为临床提供新的诊断思路,尤其适用于基层医院,对推动医疗事业的发展具有重要作用.
Study on the correlation between epicardial fat thickness and coronary heart disease and its severity during Chinese medicine treatment
Objective To explore the correlation between epicardial fat thickness(EAT)and coronary heart disease(CHD)and its severity during Chinese medicine treatment.Methods The clinical data of 300 patients who underwent coronary angiography in cardiovascular department from July 2021 to August 2023 were retrospectively analyzed.According to the results of coronary an-giography,they were divided into coronary heart disease group(200 cases)and no coronary heart disease group(hereinafter re-ferred to as"control group",100 cases).According to the number of coronary arteries involved,the CHD group was divided into a single-vessel disease group(100 cases)and a group with more than one vessel disease(100 cases).Coronary angiography and e-chocardiography were performed to compare the levels of biochemical indexes,cardiac function indexes and EAT test results of each group,and to analyze the levels of EAT and coronary heart disease biochemical and cardiac function indexes.Results There were no significant differences in total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),fasting blood glucose(FBG)and left ventricular ejection fraction(LVEF)among all groups(P>0.05).The left atrial diameter and EAT in the group with more than one vessel disease were higher than those in the group with more than one vessel disease and the control group,with statistical difference(P<0.05).Pearson correlation analysis showed that EAT was positively correlated with age,TG level and left atrial diameter of patients(r=0.312,0.418,0.834,P=0.003,<0.001,<0.001),and negatively correlated with HDL-C(r=-0.229,P=0.001).Conclusion There is a certain correlation between the EAT assessment and the severity of coronary heart disease during the treatment of traditional Chinese medicine.The changes in the EAT level can be judged by observing the changes in the condition of patients with coronary heart disease.In addition,the ultrasound examination is simple,non-invasive and fast,which is suitable for the early screening of coronary heart disease and provides new diagnostic ideas for the clinic,especially for primary hospitals.It plays an important role in promoting the development of medical treatment.

Coronary heart diseaseGuben saving heart prescriptionEpicardial fat thicknessEchocardiographycorrelation

林云、陈天兵、熊剑

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江西中医药大学附属医院

江西省儿童医院,南昌 330006

冠心病 固本救心方 心外膜脂肪厚度 超声心动图 相关性

2024

江西医药
江西省医学会

江西医药

影响因子:0.793
ISSN:1006-2238
年,卷(期):2024.59(11)