Study on the correlation between epicardial fat thickness and coronary heart disease and its severity during Chinese medicine treatment
Objective To explore the correlation between epicardial fat thickness(EAT)and coronary heart disease(CHD)and its severity during Chinese medicine treatment.Methods The clinical data of 300 patients who underwent coronary angiography in cardiovascular department from July 2021 to August 2023 were retrospectively analyzed.According to the results of coronary an-giography,they were divided into coronary heart disease group(200 cases)and no coronary heart disease group(hereinafter re-ferred to as"control group",100 cases).According to the number of coronary arteries involved,the CHD group was divided into a single-vessel disease group(100 cases)and a group with more than one vessel disease(100 cases).Coronary angiography and e-chocardiography were performed to compare the levels of biochemical indexes,cardiac function indexes and EAT test results of each group,and to analyze the levels of EAT and coronary heart disease biochemical and cardiac function indexes.Results There were no significant differences in total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C),high density lipoprotein cholesterol(HDL-C),fasting blood glucose(FBG)and left ventricular ejection fraction(LVEF)among all groups(P>0.05).The left atrial diameter and EAT in the group with more than one vessel disease were higher than those in the group with more than one vessel disease and the control group,with statistical difference(P<0.05).Pearson correlation analysis showed that EAT was positively correlated with age,TG level and left atrial diameter of patients(r=0.312,0.418,0.834,P=0.003,<0.001,<0.001),and negatively correlated with HDL-C(r=-0.229,P=0.001).Conclusion There is a certain correlation between the EAT assessment and the severity of coronary heart disease during the treatment of traditional Chinese medicine.The changes in the EAT level can be judged by observing the changes in the condition of patients with coronary heart disease.In addition,the ultrasound examination is simple,non-invasive and fast,which is suitable for the early screening of coronary heart disease and provides new diagnostic ideas for the clinic,especially for primary hospitals.It plays an important role in promoting the development of medical treatment.