Research progress in the interaction mechanism between members of the insect heat shock protein family
As one of the most important proteins for organisms to resist external stress,heat shock proteins play an irreplaceable role in species survival and even population reproduction.Research has shown that heat shock proteins are closely involved in various steps of protein maturation,including protein folding,protein translocation,and protein assembly.Some members also participate in the regulation of transcription factors and protein kinases.As for most other proteins,there are also interactions among members of the heat shock protein family,and some heat shock proteins even require the cooperation of other family members to fully exert their effects.Therefore,the study of the interaction mechanism between members of the heat shock protein family is of great significance for understanding the function and mechanism of action of heat shock proteins.At present,the interaction mechanisms extensively studied include the direct interaction and functional collaboration between Hsp90 and Hsp70,the pairing and binding of Hsp70 and Hsp40 to exert specific functions,and the joint participation of Hsp60 and Hsp10 in the folding and assembly of transport proteins.This article provides a review of the interaction mechanisms reported by far between Hsp90 and Hsp70,Hsp70 and Hsp40,and Hsp60 and Hsp10,particularly their related research progress in insects.This article aims to provide references for further in-depth research on the function and mechanism of insect heat shock proteins,and to provide inspiration for pest control and beneficial insect utilization.
heat shock proteinprotein-protein interactionprotein folding and assemblyinteraction mechanismpest control
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维普
