糖尿病及降糖药物对骨代谢及骨折影响的相关研究进展
Research advances in effects of diabetes mellitus and hypoglycemic drugs on bone metabolism and fracture
谭文彬 1李佳 2刘明玉 1路永欣 1程雅欣2
作者信息
- 1. 南部战区总医院内分泌科,广东广州 510010;南方医科大学第一临床医学院,广东广州 510515
- 2. 南部战区总医院内分泌科,广东广州 510010
- 折叠
摘要
糖尿病(diabetes mellitus,DM)与骨质疏松症(osteoporosis,OP)共病话题一直备受关注.DM可通过不同环节干扰骨重塑,在DM合并OP的长期管理中,部分降糖药可能对骨代谢产生负性影响.为预防药物不良反应影响疾病发展,本文综述各型DM和各类降糖药物对骨代谢和骨折的可能影响,以期为临床医师制定DM合并OP的用药方案提供参考.
Abstract
The comorbidity of diabetes mellitus(DM)and osteoporosis(OP)has long been a topic of concern.DM can interfere with bone remodeling through different links,in the long-term management of diabetic patients with osteoporosis,some hypoglycemic drugs may affect bone metabolism in diabetic patients.In order to prevent adverse drug reactions from aggravating the development of the disease,this review describes the possible effects of DM and hypoglycemic drugs on bone metabolism and fracture to provide reference for clinicians on clinical medication.
关键词
糖尿病/骨质疏松症/骨代谢/骨折/降糖药物Key words
diabetes mellitus/osteoporosis/bone metabolism/fracture/hypoglycemic drugs引用本文复制引用
基金项目
国家重点研发计划(2021YFC2501701)
出版年
2024
国家科技期刊平台
NSTL
万方数据