慢性前列腺炎伴不育与人体微生物组关系研究进展
Research advances in relationship between infertility associated with chronic prostatitis and human microbiological group
苏旭珍 1项瑞君 2张强 2张春雷 3张斌 3常德辉3
作者信息
- 1. 甘肃中医药大学第一临床医学院,甘肃兰州 730030;联勤保障部队第940医院泌尿外科,甘肃兰州 730050;甘肃省干细胞与基因药物重点实验室,甘肃兰州 730050
- 2. 甘肃中医药大学第一临床医学院,甘肃兰州 730030;联勤保障部队第940医院泌尿外科,甘肃兰州 730050
- 3. 联勤保障部队第940医院泌尿外科,甘肃兰州 730050
- 折叠
摘要
慢性前列腺炎(chronic prostatitis,CP)是泌尿生殖系统常见病、多发病之一,严重影响患者的身心健康.研究发现,CP与不育关系密切,可能与精液中炎症、氧化应激损伤等因素有关.CP患者不育的病因和发病机制目前仍不明确.近年来,有学者认为其可能与自身及性伴侣的泌尿生殖系统、肠道等的微生物组变化有关.本文从CP伴不育与人体微生物组变化的角度,对临床CP患者不育的发病机制和治疗最新进展进行综述.
Abstract
Chronic prostatitis(CP)is one of the common and frequently-occurring diseases of the genitourinary system,which seriously affects the physical and mental health of patients.Studies have found that there is a close relationship between CP and infertility,which may be related to inflammation in semen,oxidative stress damage and other factors.However,the etiology and pathogenesis of infertility in patients with CP are still unclear.In recent years,some scholars believe that it may be related to the changes of human microflora such as genitourinary system and intestinal tract of themselves and their sexual partners.Therefore,this article reviews the changes of CP associated infertility and human microflora in order to understand the pathogenesis and treatment of infertility in clinical CP patients.
关键词
慢性前列腺炎/不育/人体微生物组/炎症/治疗Key words
chronic prostatitis/infertility/human microbiological group/inflammation/treatment引用本文复制引用
基金项目
军队项目(21BJZ43)
军队项目(21JSZ13)
甘肃省自然科学基金(22JR5RA001)
军队项目(2021yxky017)
甘肃省自然科学基金(23JRRA531)
出版年
2024
国家科技期刊平台
NSTL
万方数据