多学科协作诊治妊娠合并胸段硬脊膜恶性黑色素瘤1例
Multidisciplinary collaboration in diagnosis and treatment of pregnancy complicated with malignant melanoma of thoracic spinal cord:A case report
王晓萍 1游艳琴 1谢潇潇 1胡凌云 1卢彦平2
作者信息
- 1. 解放军总医院第一医学中心妇产科,北京 100853
- 2. 解放军总医院第七医学中心妇产医学部,北京 100010
- 折叠
摘要
中枢神经系统黑色素瘤发病率低、预后差,娠合并胸段硬脊膜恶性黑色素瘤罕见,且缺乏治疗成功案例的相关报道.本文报告 1例妊娠合并胸段硬脊膜恶性黑色素瘤,患者因妊娠晚期双下肢麻木、感觉减退入院.解放军总医院第一医学中心产科联合神经内科、神经外科、病理科等多学科协作成功诊治:孕 37+2 周剖宫产分娩,新生儿生后 1 min、5 min的Apgar评分为10分;序贯实施胸椎管内病灶切除,病理提示为硬脊膜恶性黑色素瘤.该病例随访7年仍存活,母儿结局和预后良好.
Abstract
The incidence rate of melanoma in the central nervous system is low and the prognosis is poor.However,the occurrence of malignant melanoma in the thoracic spinal dura during pregnancy is rare,and there are no relevant reports of successful treatment cases.This paper reports a case of pregnancy complicated with malignant melanoma of thoracic spinal cord,who had been admitted due to numbness and decreased sensation in both lower limbs during late pregnancy.The patient had been successfully diagnosed and treated through multidisciplinary collaboration among obstetrics department,neurology department,neurosurgery department,pathology department,and other disciplines.The delivery was performed by cesarean section at 37+2 weeks of pregnancy,and the newborn had an Apgar score of 10 at 1 minute and 5 minutes after birth;Sequential resection of lesions within the thoracic spinal canal was performed,with pathological findings indicating malignant melanoma of thoracic spinal cord.The patient has been followed up for 7 years and still survived,with good maternal and fetal outcomes and prognosis.
关键词
硬脊膜恶性黑色素瘤/妊娠/合并症/多学科协作/治疗Key words
spinal malignant melanoma/pregnancy/complication/multidisciplinary collaboration/treatment引用本文复制引用
出版年
2024
国家科技期刊平台
NSTL
万方数据