首页|分离自北京口岸进出口食品的大肠埃希氏菌耐药性筛查分析

分离自北京口岸进出口食品的大肠埃希氏菌耐药性筛查分析

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为了解北京口岸进出口食品中分离的大肠埃希菌的耐药情况.采用微量肉汤稀释法,分析111株进出口食品中分离的大肠埃希菌对33种抗生素的耐药性.结果显示,在111株大肠埃希菌中,88株有耐药性,耐药率为79.3%,其中38株菌为多重耐药.头孢氨苄耐药率最高,达62.2%,四环素、萘啶酸、复方新诺明耐药率在25%~35%之间,同时检出ESBLs大肠埃希菌9株.北京口岸出口食品中分离大肠埃希氏与国内其他地区分离菌株相比菌耐药率普遍偏低,耐药谱基本一致.出口食品分离的大肠埃希菌多重耐药检出率(49.3%)远高于进口食品来源的大肠埃希菌(9.5%).在111株大肠埃希菌中,ESBLs检出率为8.2%,产ESBLs大肠埃希菌不仅有较高的耐药率且多重耐药情况严重.应继续倡导畜牧业减少抗生素的使用,合理使用高效抑菌抗生素,避免滥用.
Screening analysis of antibiotic resistance of Escherichia coli isolated from imported and exported food at Beijing port
To understand the drug resistance of Escherichia coli isolated from imported and exported food at Beijing port.A total of 111 strains of Escherichia coli was subjected to 33 antibiotic susceptibility tests using a micro broth dilution method.Among the 111 strains of Escherichia coli,88 strains showed resistance,with a resistance rate of 79.3%.Among them,38 strains were multidrug-resistant.The highest resistance rate of Escherichia coli to cephalosporin was found at the Beijing port,with a resistance rate of 62.2%.The resistance rates to tetracycline,naphthoic acid,and compound sulfamethoxazole ranged from 25%to 35%,and 9 strains of ESBLs Escherichia coli were detected.Compared with strains isolated from other regions in China,the resistance rate of Escherichia coli isolated from exported food at Beijing port is generally lower,and the resistance spectrum is basically consistent.The detection rate of multidrug-resistant Escherichia coli isolated from export-ed food(49.3%)is much higher than that of Escherichia coli from imported food sources(9.5%).The detection rate of ES-BLs in 111 strains of Escherichia coli is 8.2%,and ESBLs producing Escherichia coli not only has a high resistance rate but also has a serious situation of multiple drug resistance.We should continue to advocate for animal husbandry to reduce the use of antibiotics,use efficient antibacterial antibiotics reasonably,and avoid abuse.

Escherichia coliDrug resistanceESBLsImported and exported food

赵晓娟、刘婧洋、魏咏新、张西萌、马丹、魏海燕

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中国海关科学技术研究中心 北京 100026

首都医科大学燕京医学院

大肠埃希菌 耐药性 超广谱β-内酰胺酶 进出口食品

中国认证认可协会科技计划项目海关总署科研项目

2022CCAAKY132021HK215

2024

质量安全与检验检测
中国检验检疫科学研究院

质量安全与检验检测

影响因子:0.399
ISSN:2096-8876
年,卷(期):2024.34(1)
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