高效液相色谱-串联质谱法在农药检测中的应用
Factors affecting the drawing of standard curves by high performance liquid chromatography tandem mass spectrometry and their correction
刘小丽 1李青 2张艳丽1
作者信息
- 1. 鹤壁市产品质量检验检测中心 河南鹤壁 458030
- 2. 焦作市产品质量检验检测中心
- 折叠
摘要
用GB 23200.121-2021《食品安全国家标准 植物源性食品中331种农药及其代谢物残留量的测定液相色谱-质谱联用法》中方法,绘制标准工作曲线,得到的部分农药相关系数R值达不到0.995.通过实验发现,选择合适的浓度点、正确的离子对和电压值可以使标准工作曲线的相关系数R值达到0.999 9或更高.
Abstract
In GB 23200.121-2021"National food safety standard determination of 331 pesticides and metabolites residues in foods of plant origin liquid chromatography-tandem mass spectrometry method",a standard working curve is plotted,and the correlation coefficient R value of some pesticides does not reach 0.995.Through experiments,it was found that selecting ap-propriate concentration points,correct ion pairs,and voltage values can achieve a correlation coefficient R value of 0.999 9 or higher for the standard working curve.
关键词
液质联用仪标准工作曲线离子对/响应值/基质效应Key words
LC-MS standard curve ion pair/Response value/Matrix effect引用本文复制引用
出版年
2024
NETL
NSTL
万方数据