Factors affecting the drawing of standard curves by high performance liquid chromatography tandem mass spectrometry and their correction
In GB 23200.121-2021"National food safety standard determination of 331 pesticides and metabolites residues in foods of plant origin liquid chromatography-tandem mass spectrometry method",a standard working curve is plotted,and the correlation coefficient R value of some pesticides does not reach 0.995.Through experiments,it was found that selecting ap-propriate concentration points,correct ion pairs,and voltage values can achieve a correlation coefficient R value of 0.999 9 or higher for the standard working curve.
LC-MS standard curve ion pairResponse valueMatrix effect
NETL
NSTL
万方数据
