Objective To explore the effect of percutaneous internal fixation system on the therapeutic effect and stress response of traumatic thoracolumbar fractures,serum glial fibrillary acidic protein(GFAP),neuron specific enolase(NSE)levels.Methods Eighty-four patients with traumatic thoracolumbar fractures in our hospital from February 2017 to February 2019 were selected as the study subjects,and all were treated with pedicle internal fixation system.They were divided into two groups according to different surgi-cal methods.Forty cases were used traditional surgical approach,44 cases were used percutaneous internal fixation system,which were respectively set as the control group and the observation group.The surgical indicators,follow-up indicators,stress response-related in-dicators,and serum NSE and GFAP levels between the two groups were compared.Results Compared with the control group,the ob-servation group had significantly lower intraoperative blood loss,less time to get out of bed,and shorter hospital stay(P＜0.05).The difference in operation time was not significant(P＞0.05).Compared with those preoperatively,the visual analogue scale(VAS)and Cobb angle of pain of the two groups decreased significantly on the 7th day after surgery and in the last follow-up,and the ratio of the height of the anterior edge of the injured vertebrae increased significantly.The VAS score of the observation group was lower than that of the control group on the 7th day after surgery(P＜0.05).However,there was no statistically significant difference in imaging indi-cators between groups in each period(P＞0.05).The levels of adrenaline and norepinephrine one day and one week after surgery were higher than those before surgery,and serum NSE and GFAP levels of two groups were lower than those before surgery(P＜0.05).However,the indicators in the observation group were significantly different from those in the control group one day and one week after operation(P＜0.05).Conclusion Percutaneous internal fixation system for the treatment of traumatic thoracolumbar fractures can a-chieve the same deformity correction and internal fixation effects as the traditional surgical approach,but the former has less early pain and can reduce the early postoperative stress response and spinal cord and nerve micro-injury.
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