颈腰痛杂志2024,Vol.45Issue(1) :112-115.DOI:10.3969/j.issn.1005-7234.2024.01.023

创伤性颈脊髓损伤患者住院期间并发肺部感染的风险因素分析

Risk factors for pulmonary infection in patients with traumatic cervical spinal cord injury during hospitalization

冯爱星 冯爱云 梁明哲
颈腰痛杂志2024,Vol.45Issue(1) :112-115.DOI:10.3969/j.issn.1005-7234.2024.01.023

创伤性颈脊髓损伤患者住院期间并发肺部感染的风险因素分析

Risk factors for pulmonary infection in patients with traumatic cervical spinal cord injury during hospitalization

冯爱星 1冯爱云 1梁明哲1
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作者信息

  • 1. 郑州市第一人民医院急诊科,河南 郑州 450000
  • 折叠

摘要

目的 观察创伤性颈脊髓损伤(traumatic cervical spinal cord injury,TCSCI)患者住院期间的肺部感染发生情况,并分析其潜在的风险因素.方法 回顾性分析我院2018 年3 月~2022 年3 月收治的 110 例TCSCI患者临床资料,根据住院期间是否并发肺部感染,分为感染组和非感染组.统计两组患者的潜在相关资料,并进行组间单因素分析和多因素Logistic回归分析.结果 110 例中,41 例(37.3%)住院期间发生肺部感染,发生于入院后的 3~10 d、平均4.3 d;其中,35 例(85.4%)经积极治疗后好转,6 例(14.6%)最终因并发呼吸衰竭死亡.多因素Logistic回归模型分析证实:呼吸机辅助通气(OR =6.498,P<0.001)、血清Na+水平(OR=0.693,P=0.001)和ASIA分级(OR =0.386,P<0.001)均是TCSCI患者住院期间并发肺部感染的独立影响因素.结论 TCSCI患者住院期间肺部感染的发生率较高,呼吸机辅助通气可增加肺部感染的风险;而ASIA分级较高、血清Na+水平趋于正常者,其并发肺部感染的风险相对较低.

Abstract

Objective To observe the incidence of pulmonary infection in patients with traumatic cervical spinal cord injury(TCS-CI)during hospitalization,and analyze its potential risk factors.Methods The clinical data of 110 patients with TCSCI admitted to our hospital from March 2018 to March 2022 were retrospectively analyzed,and the patients were divided into infection and non infec-tion groups according to whether they had concurrent pulmonary infection during hospitalization.The potential relevant data were col-lected from two groups of patients and inter group univariate analysis and multivariate logistic regression analysis was conducted.Re-sults Of 110 cases,41(37.3%)developed pulmonary infection during hospitalization,which occurred 3 to 10 days after admission,mean 4.3 days;of these,35(85.4%)improved with active treatment,and the other 6(14.6%)eventually died due to intercurrent respiratory failure.Multivariate logistic regression model analysis confirmed that ventilator-assisted ventilation(OR =6.498,P<0.001),serum Na+level(OR=0.693,P=0.001)and ASIA grade(OR=0.386,P<0.001)were all independent influencing fac-tors for lung infection in TCSCI patients during hospitalization.Conclusion The incidence of lung infection in TCSCI patients during hospitalization is high,and ventilator-assisted ventilation can increase the risk of lung infection.The risk of pulmonary infection is rela-tively low in patients with high ASIA grade and normal serum Na+level.

关键词

颈脊髓损伤/颈椎创伤/肺部感染/呼吸机辅助通气/低钠血症

Key words

cervical spinal cord injury/cervical trauma/pulmonary infection/ventilator assisted ventilation/hyponatremia

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出版年

2024
颈腰痛杂志
安徽医科大学

颈腰痛杂志

CSTPCD
影响因子:1.006
ISSN:1005-7234
参考文献量6
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