Objective To investigate the correlation between sagittal imbalance(SI)of thoracolumbar osteoporotic vertebral com-pression fracture(OVCF)and re collapse after percutaneous vertebroplasty(PVP).Methods The data of 167 patients with OVCF who received PVP treatment in our hospital from January 2018 to December 2020 were analyzed.According to whether PVP collapsed again after surgery,the patients were divided into collapse group and non collapse group.The incidence of Si before operation and the independent effect of Si on the re collapse after PVP were observed.Whether the changes of TKA and SV A values in patients with SI at different times were observed.Results Among 167 patients who were followed up to 12 months,38 patients met the definition criteria of re collapse and were included in the re collapse group.The remaining 129 patients were included in the non collapse group.The preoperative SV A and Si of patients in the re collapse group were higher than those in the non collapse group(P<0.05).There were significant differences in bone mineral density,previous OVCF history,bone cement leakage,bone cement lumps,lack of bone cement in the fracture area,dynamic mobility,thoracolumbar kyphosis angle between the re collapse group and the non re collapse group(P<0.05).Multivariate logistic analysis showed that preoperative Si was an independent risk factor for re collapse of vertebral bodies strengthened with bone cement(P<0.05).TKA and SVA of patients in Si and non Si groups showed a progressive trend at different times,and there was significant difference between the two groups(F=48.072,36.492,11.457,9.122,P<0.05).Compared with the non Si Group,the difference of TKA and SV A in the Si group was higher than that in the non Si Group at the follow-up of 1 year,and the difference was statistically significant(t=5.082,4.377,P<0.05).Conclusion SI,bone density,dynamic mobility,mas-sive distribution of bone cement,and insufficient bone cement dispersion in fracture area are risk factors for vertebral body re collapse after PVP in patients with thoracolumbar OVCF.SI is related to the progress of sagittal position after surgery,and potential SI patients should be strictly managed to reduce vertebral body re collapse after surgery.