摘要
目的 分析青少年特发性脊柱侧凸(AIS)的影响因素并建立预测模型.方法 随机选取2021年5月至2023年5月南京同仁医院于社区筛查出的100例AIS患者(侧凸组),并按照1∶3比例随机抽取300例健康青少年人群作为对照组,对比两组一般资料、学习与生活相关资料、生物力学测量结果等,经单因素及多因素Logistic回归法分析AIS的影响因素.结果 多因素Logistic回归分析显示,女性、年龄＞14岁、睡姿为俯卧位、睡眠时间≥10 h、舞蹈训练、长短腿、扁平足、高低肩为AIS的独立危险因素,BMI 24～28 kg/m2、户外运动次数≥3次/d为AIS的保护因素(P＜0.05).年龄、BMI、睡眠时间预测AIS风险的ROC曲线下面积AUC分别为0.723、0.765、0.608.构建风险预测模型:Log(P)=2.506 ×女性+1.305 ×年龄-3.288 × BMI+0.718 ×睡姿+0.659 ×睡眠时间-3.289 ×户外运动次数+0.586 ×舞蹈训练+2.059 ×长短腿+0.912 ×扁平足+1.428 ×高低肩-33.372.结论 女性、年龄＞14岁、睡姿为俯卧位、睡眠时间≥10 h、舞蹈训练、长短腿、扁平足、高低肩是影响AIS的危险因素,BMI在24～28 kg/m2、户外运动次数≥3次/d为保护因素,早期应据此开展相关干预以减少或延缓疾病进展.
Abstract
Objective To analyze the influencing factors of adolescent idiopathic scoliosis(AIS)and establish a prediction mod-el.Methods A total of 100 patients with AIS in communities,who were screened out by Nanjing Tongren Hospital from May 2021 to May 2023 were randomly selected and defined as the scoliosis group.At the same time,300 healthy adolescents were randomly selected as the control group.General data,study and life related data,and biomechanical measurements of the two groups were compared.Un-ivariate analysis and multivariate logistic regression analysis were conducted to identify the influencing factors of AIS.Results Multi-variate logistic regression analysis found that female,age＞14 years,sleeping in prone position,sleep time ≥ 10 h,dance training,unequal legs,flatfoot,and high and low shoulders were independent risk factors for AIS.BMI of 24-28 kg/m2 and frequency of out-door exercise ≥3 times/d were protective factors for AIS(P＜0.05).The area under the ROC curve(AUC)values of age,BMI and sleep time for predicting the risk of AIS were 0.723,0.765 and 0.608.The risk prediction model established was as follow:Log(P)=2.506 × female+1.305 × age-3.288 × BMI+0.718 × sleeping posture+0.659 × sleep time-3.289 × frequency of outdoor exercise+0.586 × dance training+2.059 × unequal legs+0.912 × flatfoot+1.428 × unequal shoulder height-33.372.Conclusion Fe-male,age＞14 years,sleeping in prone position,sleeping time≥10 h,dance training,unequal legs,flatfoot,and high and low shoulders are risk factors influencing AIS.BMI of 24～28 kg/m2 and frequency of outdoor exercise ≥ 3 times/d are protective factors.Early intervention should be carried out based on these factors to reduce or delay disease progression.
维普
万方数据