Objective To investigate the neuropathological characteristics of low back pain in patients with osteoporotic vertebral fracture(OVF).Methods 83 OVF patients who were admitted to our hospital from March 2020 to December 2021 with chronic low back pain as their main complaint were selected as the study subjects.The severity of low back pain and its impact on activities of daily living(ADL)were assessed by the brief pain inventory(BPI),and the neuropathological components of patients'low back pain were assessed by the Leeds assessment of neuropathic symptoms and signs(LANSS)and the pain detect questionnaire(PD-Q),the charac-teristic manifestations of LANSS and PD-Q were observed.Results The severity of BPI in 83 patients was 3-8 points,including 41 cases of mild pain(1-4 points),30 cases of moderate pain(5-6 points),and 12 cases of severe pain(≥7 points).BPI interfer-ence index was 2-9 points,51 cases were low interference(1-4 points)and 32 cases were high interference(5-10 points).There was no significant difference in BPI pain and BPI interference between single segment and multi segment OVF patients(P＞0.05).The PD-Q scores of 83 patients ranged from 3 to 29,including 63 patients with nociceptive pain(0 to 12 points),13 patients with mixed pain(13 to 18 points),and 7 patients with neuropathic pain(≥19 points).The scores of LANSS ranged from 4 to 18,inclu-ding 61 cases of non neuropathic pain(＜12 points)and 22 cases of neuropathic pain.There was no significant difference in PD-Q and LANSS results between single segment and multi segment OVF patients(P＞0.05).In the single segment OVF patients,the PD-Q and LANSS scores of thoracic OVF patients were higher than those of lumbar OVF patients,and the difference was statistically signif-icant(P＜0.05).Among the patients with multi-level OVF,the PD-Q score of lumbar multi-level OVF was higher than that of thorac-ic and thoracolumbar(P＜0.05),and there was no significant difference in LANSS scores among thoracic,lumbar and thoracolumbar OVF patients(P＞0.05).There was no significant correlation between SDI and pd-q and LANSS(r=0.172,0.203,P＞0.05).Conclusion Neuropathic pain of OVF is common in single segment thoracic OVF and lumbar multiple OVF.Attention should be paid to neuropathic pain evaluation in OVF patients in order to formulate the best pain relief strategy.
关键词
骨质疏松性椎体骨折/神经病理性疼痛/腰背痛
Key words
osteoporotic vertebral fracture/neuropathic pain/low back pain
维普
万方数据