Objective To investigate the prognostic factors of long-term mechanical ventilation(MV)-dependent respiratory fail-ure after cervical spinal cord injury(CSCI).Methods 41 patients with CSCI who underwent decompression surgery in our hospital from January 2018 to September 2021 were selected as the research objects.According to whether they were successfully offline,the patients were divided into MV dependent(MVDC)and successful offline.The differences of clinical data between the two groups were observed,and the risk factors affecting mvdc were observed by multivariate logistic analysis.Results There was no significant differ-ence in MV mode and final airway time between mvdc and patients who were successfully weaned(P＞0.05).The MV time and ICU time of mvdc patients were higher than those of successful offline patients,and the survival rate was lower than that of successful offline patients(P＜0.05).The adverse factors affecting MV weaning included higher Asia grade and complete spinal cord injury(P＜0.05).There were significant differences in the maximum spinal cord compression level,injured segment and MCC between mvdc pa-tients and MV patients with successful weaning(P＜0.05).There was no significant difference in the number of segments of T2WI signal change,morphology+DLC score,SLIC score and Mr performance between the two groups(P＞0.05).Multivariate logistic a-nalysis showed that complete spinal cord injury,C3-C6 segmental injury and MCC≥50.83％were the risk factors affecting mvdc(P＜0.05).MCC predicted mvdc with sensitivity of 0.833,specificity of 0.826,cut-off value of 50.83％,area under the curve of 0.838 and 95％CI of 0.690-0.934.Conclusions Complete spinal cord injury,MCC and C3-C6 injury are important factors of mvdc,which is helpful to predict the outcome of respiratory function recovery in MV patients with respiratory failure after CSCI.
维普
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