Application effect of IOC1 combined with IOC2 monitoring in patients with persistent vegetative state and minimally conscious state during general anesthesia
Objective To analyze the application effect of consciousness index(IOC1)and nociceptive sen-sitivity index(IOC2)monitoring in patients with persistent vegetative state(PVS)the minimally conscious state(MCS)during general anesthesia.Methods Fifty patients with PVS or MCS who underwent surgery in this hospital from March 2022 to September 2023 were randomly divided into the control group and the con-sciousness index monitoring group,25 cases in each group.Routine monitoring was performed in the control group,and IOC1 and IOC2 were monitored in the consciousness index monitoring group at the same time.Mean arterial pressure(MAP)and heart rate(HR)of two groups were collected before anesthesia(T0),after induction(T1),after intubation(T2),5 min after surgery(T3)and at the end of surgery(T4).The time in-dex,dosage of remifentanil and sevoflurane,incidence of hypotension and sinus bradycardia during anesthesia were recorded.Results The MAP of T1,T2,T3,T4 in the control group was lower than that of T0,and the MAP of T3 was lower than that of T1 and T2,and the MAP of T4 was higher than that of T3,and the differ-ences were statistically significant(P＜0.05).The MAP of T1,T2,T3 and T4 in the consciousness index mo-nitoring group was lower than that of T0,and the MAP of T3 and T4 was higher than that of T1 and T2,and the differences were statistically significant(P＜0.05).The HR of T1,T2,T3,T4 in the control group was lower than that of T0,and the HR of T3 was lower than that of T1 and T2,and the HR of T4 was higher than that of T3,and the differences were statistically significant(P＜0.05).The HR of T1,T2,T3,T4 in the con-sciousness index monitoring group was lower than that of T0,and the HR of T4 was higher than that of T1,T2,T3,and the differences were statistically significant(P＜0.05).The extubation time and anesthesia recov-ery room retention time in the consciousness index monitoring group were shorter than those in the control group,the dosage of remifentanil and sevoflurane were less than those in the control group,and the incidence of hypotension in the consciousness index monitoring group was lower than that in the control group,and the differences were statistically significant(P＜0.05).Conclusion In patients with PVS and MCS,IOC1 and IOC2 monitoring can reduce the dosage of anesthetic drugs,stabilize blood pressure and HR,accurately predict the time of extubation and shorten the retention time of anesthesia recovery room.
deep sedationnociceptive paincritical care outcomegeneral anesthesiaquantitative consciousness index
万方数据
维普
