Application effect of traditional Chinese medicine"lung intestinal combined treatment"combined with bifidobacterium live bacteria capsule in patients with severe pneumonia complicated with gastrointestinal dysfunction
Objective To explore the application effect of traditional Chinese medicine"lung intestinal combined treatment"combined with bifidobacterium live bacteria capsule in patients with severe pneumonia complicated with gastrointestinal dysfunction.Methods The clinical data of 153 patients with severe pneumo-nia complicated with gastrointestinal dysfunction admitted to the intensive care unit(ICU)of this hospital from June 2019 to June 2023 were retrospectively analyzed,and they were divided into study group(77 cases)and control group(76 cases)according to different treatment regiments.All patients received basic treatment,the control group was treated with bifidobacterium live bacteria capsule,and the research group was treated with traditional Chinese medicine"lung intestinal combined treatment"on the basis of the control group.Baseline data and relevant scores[Acute Physiological And Chronic Health Conditions Ⅱ(APACHE Ⅱ)score,Sequential Organ Failure Assessment(SOFA)score,Gastrointestinal Failure(GIF)score,Clinical Pul-monary Infection Scale(CPIS)score],gastrointestinal function indicators[gastrin(GAS),motilin(MTL),D-lactic acid,diamine oxidase(DAO)],inflammatory indicators[procalcitonin(PCT),C-reactive protein(CRP)],mortality were compared between the two groups.Results The duration of ICU stay and mechanical ventilation in the study group were significantly shorter than those in the control group,and the oxygenation index(PaO2/FiO)in the two groups after treatment was higher than that before treatment,and it in the study group was higher than that in the control group,and the differences were statistically significant(P＜0.05).After treatment,APACHE Ⅱ score,SOFA score,GIF score,CPIS score and the levels of GAS,D-lactic acid,DAO,PCT and CRP in two groups were lower than before treatment,and those in the study group were lower than those in the control group,and the differences were statistically significant(P＜0.05).After treatment,the MTL level of the two groups was higher than before treatment,and that in the study group was higher than that in the control group,and the differences were statistically significant(P＜0.05).There was no sig-nificant difference in mortality between the two groups(P＞0.05).Conclusion Based on bifidobacterium live bacteria capsule combined with traditional Chinese medicine"lung intestinal combined treatment"can effec-tively shorten the ICU stay and mechanical ventilation time of patients,improve PaO2/FiO,restore gastroin-testinal function and reduce the level of inflammation indicators.
lung intestinal combined treatmentbifidobacterium live bacteria capsulesevere pneumo-niagastrointestinal dysfunctionmechanical ventilation
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