Progress in the clinical diagnosis and treatment of Helicobacter pylori gastritis complicated with small intestinal bacterial overgrowth
Gastrointestinal microbiota is inseparable from the health of the host,in recent years,studies have found that both Helicobacter pylori(Hp)gastritis and intestinal bacterial overgrowth(SIBO),and their clinical symptoms overlap to a certain extent.Therefore,it is believed that there is a certain relationship be-tween Hp gastritis and SIBO,which is rarely studied in clinical diagnosis and treatment at present.This paper describes the occurrence and pathophysiological mechanism of Hp gastritis complicated with SIBO.The ad-vantages and disadvantages of bacterial culture,breath test and novel detection techniques in diagnosing Hp gastritis with SIBO are discussed,and the efficacy of Hp eradication therapy and probiotic therapy in SIBO are also discussed.The clinical diagnosis and treatment of Hp gastritis with SIBO remain difficult,and more high-quality clinical studies are needed to guide medication regimens in the future.