Objective To analyze the risk factors of adjacent vertebral fractures(AVF)in osteoporotic vertebral compression fracture(OVCF)patients after percutaneous vertebral augmentation(PVA),and to construct a simple score scale.Methods The clinical data of 313 OVCF patients treated with PVA from January 2018 to January 2022 were retrospectively analyzed,and the patients were divided into AVF group(n=86)and control group(n=227)according to whether AVF occurred after surgery.Independent risk factors associated with AVF were obtained through univariate analysis and multivariate logistic regression analysis,and a prediction model of AVF risk was established.A simple score scale was constructed,and the sensitivity and specificity of the scale were evaluated by receiver operating characteristics(ROC)curve.Results Univariate analysis showed that there were statistically significant differences between the 2 groups in age,fracture history,whether treated with anti-osteoporosis medication,serum vitamin D level,vertebral HU value,paraverteinal muscle HU value,whether with intervertebral leakage of bone cement and distribution morphology of bone cement(P＜0.05).Logistic regression analysis showed that age＞77.5,without anti-osteoporosis medication treatment,presence of bone cement intervertebral leakage,and vertebral HU value ≤ 65.0 were correlated with AFV after PVA.A simple score scale for AVF risk prediction was established based on logistic regression analysis.The area under the ROC curve(AUC)of the scale was 0.758,and the sensitivity and specificity were 94.2％and 50.7％,respectively,when the score was≥3.Conclusions Age＞77.5,without anti-osteoporosis medication treatment,presence of bone cement intervertebral leakage,and vertebral HU value≤65.0 are independent risk factors for AVF after PVA.The simple score scale constructed based on this has good predictive efficacy,and can provide a reference for evaluating the risk of AVF after PVA.
维普
万方数据