Objective To investigate the appropriate timing of surgery for percutaneous kyphoplasty(PKP)in the treatment of osteoporotic vertebral compression fractures(OVCF).Methods Data of 238 OVCF patients treated with PKP from January 2022 to December 2022 were retrospectively analyzed,and these patients were divided into 3 groups according to the length of time from injury to hospitalization:early group(operation within 4 weeks after fracture),middle group(operation within 4 to 8 weeks after fracture),and late group(operation after 8 weeks after fracture).The anterior and middle heights of injured vertebrae,Cobb angle and wedge angle of injured vertebrae were measured on lateral roentgenograph,and the compression rate and the recovery rate of the height of injured vertebrae were calculated.At pre-operation,before discharge and at postoperative 6 months,pain intensity was assessed by the visual analog scale(VAS)score,and lumbar function was evaluated with the Oswestry disability index(ODI).The incidence of bone cement leakage was also recorded.Results The bone cement leakage rate was 6.3％.The compression rate of anterior height of injured vertebrae in the early group was lower than that in the middle and late groups at postoperative 1 d and 6 months,and the recovery rate of anterior height of injured vertebrae at postoperative 6 months was better than that in the middle and late groups,all with a statistical significance(P＜0.05).The compression rate of middle height of injured vertebrae in the early group was lower than that in the middle and late groups at postoperative 1 d,and the recovery rate of middle height of injured vertebrae at postoperative 1 d was better than that in the middle and late groups,all with a statistical significance(P＜0.05).The Cobb angle and wedge angle of the injured vertebrae in the early group were significantly improved at postoperative 1 d and 6 months,with statistical significances(P＜0.05).The change value of Cobb angle and wedge angle in the early group were better than those in the middle and late groups,with statistical significances(P＜0.05).The VAS score and ODI of the 3 groups were significantly improved at each follow-up time point,with statistical significances(P＜0.05).There was no significant difference in VAS score and ODI between the 3 groups at each follow-up time point(P＞0.05).Conclusion Early application of PKP treatment in patients with OVCF can lead to better restoration of vertebral height and alignment,helping to alleviate patient discomfort and improve postoperative vertebral morphology.
维普
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