The Prediction of Platelet Parameters Combined with D-dimer for Lower Extremity Venous Thromboembolism After Hip Fracture Surgery
Objective To investigate the predictive value of platelet parameters in combination with plasma D-dimer levels for assessing the risk of deep vein thrombosis(DVT)following hip fracture surgery.Methods Collection of clinical data was conducted on 110 patients with hip fractures admitted to the Department of Orthopedics at the Third Affiliated Hospital of Jinzhou Medical Univer-sity from January 1,2021 to September 31,2023.Based on the presence or absence of postoperative DVT,patients were divided into a DVT group(34 cases)and a non-DVT group(76 cases).General clinical data along with platelet count(PLT),platelet distri-bution width(PDW),platelet-larger cell ratio(P-LCR),and D-dimer levels were collected and recorded for both groups.Statisti-cal analysis was performed using SPSS version 26.0 software.Multivariate Logistic regression model was used to analyze the correlation between relevant indicators and the risk of DVT after hip fracture.ROC curve was drawn to analyze the diagnostic value of platelet pa-rameters,D-dimer and combined factors on the risk of postoperative DVT after hip fracture,with P＜0.05 as a statistically significant difference.Results The PLT level in DVT group was significantly lower than that in no DVT group,and the difference was statistical-ly significant(P＜0.05)and the P-LCR,PDW and plasma D-dimer levels in DVT group were significantly higher than that in no DVT group,and the differences were statistically significant(P＜0.05);the occurrence of postoperative DVT was used as the de-pendent variable,and the diabetes history,D-dimer,PLT,PDW and P-LCR with statistically significant differences in univariate a-nalysis were used as independent variables.Multivariate logistic regression andysis was performed.The results showed that the in-crease of D-dimer,PDW and P-LCR and the decrease of PLT were all independent risk factors for DVT after hip fracture,and the differences were statistically significant(P＜0.05);ROC curve analysis results showed that the area under ROC curve(AUC)of D-dimer,PLT,P-LCR and PDW were 0.703,0.704,0.739 and 0.704,respectively,while the AUC of combined detection was 0.862,which was significantly higher than that of single detection.Conclusion Both platelet parameters and D-dimer can be used as predictors of the risk of DVT after hip fracture,and their combined diagnosis value is higher.
万方数据
维普
