首页|补体系统与阿尔茨海默病的相关研究现状

补体系统与阿尔茨海默病的相关研究现状

Current Research Status of the Complement System and Alzheimer's Disease

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阿尔茨海默病(alzheimer's disease,AD)是一种常见的神经变性疾病,其严重危害着老年人群的生活质量.补体系统是先天免疫系统的组成成分之一,其在神经系统炎症和神经变性疾病中起着至关重要的作用,并与阿尔茨海默病的病理过程、临床诊断、治疗都有密切的关联.本文对补体系统与AD病理机制、生化标志物、治疗方法的相关研究进行综述,以期为AD提供新的研究、诊断和治疗方向.
The Alzheimer's disease(AD)is a common neurodegenerative disease which threatening the life quality of elderly people.Complement system,which is a part of the innate immune system,plays an important role in neuroinflammation and neurode-generative diseases,and has a close relationship with the pathology,diagnose and treatment of AD.In this paper,the relevant resear-ches on the complement system and the pathological mechanism,biochemical markers and therapeutic methods of AD are reviewed,in order to provide new research,diagnosis and treatment directions for AD.

Alzheimer's Diseasecomplementbiomarker

金朗、王光明、李梦凡、张金彪、李振光

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滨州医学院第二临床学院,山东烟台 264003

威海市立医院,山东威海 264200

阿尔茨海默病 补体 生化标志物

2024

锦州医科大学学报
辽宁医学院

锦州医科大学学报

影响因子:0.802
ISSN:1674-0424
年,卷(期):2024.45(3)